- Riegel, G. F.; Payne, C.; Kass, S. R. Effects of Brønsted acid cocatalysts on the activities and selectivities of charge-enhanced thiourea organocatalysts in Friedel–Crafts and Oxa-Pictet–Spengler reactions. J. Phys. Org. Chem. 2022, 35 (11). doi.org/10.1002/poc.4321
- Riegel, G. F.; Takashige, K.; Lovstedt, A.; Kass, S. R. Charge-Activated TADDOLs: Recyclable organocatalysts for asymmetric (hetero-)Diels–Alder reactions. J. Phys. Org. Chem. 2022, 35. doi.org/10.1002/poc.4355
- Riegel, G. F.; Kass, S. R. N-Vinyl and N-Aryl Hydroxypyridinium Ions: Charge-Activated Catalysts with Electron Withdrawing Groups. J. Org. Chem. 2020, 85, 6017–6026. doi.org/10.1021/acs.joc.0c00498
George F. Riegel
Research interests
As a physical organic chemist, I am interested in structure-reactivity relationships in organic molecules. My current research involves the synthesis of novel, metal-free organocatalysts for asymmetric organic reactions. The activities of established organocatalytic scaffolds can be greatly enhanced by incorporating positively-charged centers, thereby making them more attractive alternatives to less environmentally-benign, metal-based species; this represents an important step toward making industrial chemical production greener and more sustainable.
This work entails multi-step organic synthesis, quantification of Brønsted acid acidity through reaction data and NMR, IR, and UV-vis spectroscopic methods, and the use of chiral HPLC to determine enantiomeric ratios.
If you are interested in organic synthesis, organocatalysis, chemical kinetics, and mechanism elucidation, then I have research projects for you!
Teaching interests
CHM 101 Introductory Chemistry I & Lab
Areas of interest
Scientific community outreach, Early science education, LGBTQ+ advocacyPublications
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Publications
Academic credentials
B.S., Lafayette College; M.S., Ph.D., University of MinnesotaIntegrated Science and Engineering Complex (ISEC)
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